Lupe was born and raised in Chicago, Illinois, and relocated to Southern California in June 2016. She remarried on September 22, 2012.
Coming from a large family, Lupe has three brothers and six sisters, along with over 65 nieces and nephews, great-nieces and great-nephews, and great-great-nieces and great-great-nephews. She has three children of her own; however, her son passed away at the age of 23 on December 2, 2017. Her two daughters are doing well—one is a mother of three boys and manages a European Wax Center in Illinois, while her youngest daughter works as an esthetician for the same company in a different state. Lupe also has three grandsons, aged 10, 6, and 4. Additionally, she has two stepdaughters; one is studying to become a nurse at Loyola University of Chicago, and the other is a senior in high school.
Lupe is very involved in her church and community and genuinely enjoys helping others. Her husband is a millwork carpenter by trade and currently serves as the General Foreman for the millwork construction of the Lucas Museum of Narrative Art in Los Angeles, California.